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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ILKAP
All Species:
30
Human Site:
S140
Identified Species:
47.14
UniProt:
Q9H0C8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0C8
NP_110395.1
392
42907
S140
E
E
C
R
P
P
S
S
L
I
T
R
V
S
Y
Chimpanzee
Pan troglodytes
XP_001152781
553
60157
S301
E
E
C
R
P
P
S
S
L
I
T
R
V
S
Y
Rhesus Macaque
Macaca mulatta
XP_001094705
590
64766
S338
E
E
C
R
P
P
S
S
L
I
T
R
V
S
Y
Dog
Lupus familis
XP_543305
401
43921
S140
E
E
C
R
P
P
S
S
L
I
T
R
V
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0F6
392
42756
S140
Q
E
C
N
P
P
S
S
L
I
T
R
V
S
Y
Rat
Rattus norvegicus
Q9Z1Z6
392
42726
S140
Q
E
C
N
P
P
S
S
L
I
T
R
V
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513557
590
63726
S183
E
D
C
K
P
L
S
S
L
I
T
R
V
S
Y
Chicken
Gallus gallus
XP_422661
389
42657
S137
E
E
C
Q
P
L
P
S
Q
V
T
R
V
S
Y
Frog
Xenopus laevis
NP_001086890
344
37998
F114
G
G
T
R
A
S
R
F
A
A
Q
N
L
H
R
Zebra Danio
Brachydanio rerio
NP_001082973
129
14081
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496370
242
26827
D12
S
R
K
R
S
S
D
D
L
I
D
N
S
D
E
Sea Urchin
Strong. purpuratus
XP_001180671
354
39861
H121
F
Y
A
V
Y
D
G
H
S
G
D
K
A
S
K
Poplar Tree
Populus trichocarpa
XP_002321498
266
28901
A36
D
G
H
G
G
R
L
A
A
E
Y
A
Q
K
N
Maize
Zea mays
NP_001130289
360
39005
H126
H
F
A
I
Y
D
G
H
G
G
R
L
A
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT1
351
38467
L120
Y
D
G
H
G
G
R
L
A
A
E
F
A
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
65
94.2
N.A.
95.1
95.1
N.A.
60.1
84.1
58.1
23.7
N.A.
N.A.
N.A.
28.8
47.7
Protein Similarity:
100
70.5
65.2
95.2
N.A.
97.6
96.9
N.A.
62.8
88.5
72.6
29.3
N.A.
N.A.
N.A.
42.5
65
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
66.6
6.6
0
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
80
13.3
0
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
26.7
33.1
N.A.
32.4
N.A.
N.A.
Protein Similarity:
38.2
53.8
N.A.
52.8
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
7
0
0
7
20
14
0
7
20
7
0
% A
% Cys:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
0
14
7
7
0
0
14
0
0
7
7
% D
% Glu:
40
47
0
0
0
0
0
0
0
7
7
0
0
0
7
% E
% Phe:
7
7
0
0
0
0
0
7
0
0
0
7
0
0
0
% F
% Gly:
7
14
7
7
14
7
14
0
7
14
0
0
0
0
0
% G
% His:
7
0
7
7
0
0
0
14
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
54
0
0
0
0
0
% I
% Lys:
0
0
7
7
0
0
0
0
0
0
0
7
0
14
14
% K
% Leu:
0
0
0
0
0
14
7
7
54
0
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
0
14
0
0
7
% N
% Pro:
0
0
0
0
54
40
7
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
7
0
0
0
0
7
0
7
0
7
0
0
% Q
% Arg:
0
7
0
40
0
7
14
0
0
0
7
54
0
0
7
% R
% Ser:
7
0
0
0
7
14
47
54
7
0
0
0
7
60
0
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
54
0
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
7
0
0
54
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
14
0
0
0
0
0
7
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _